Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LDLR | P01130 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970916 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AALDH1A1GAALDLR | |
| SCHEMBL8395193 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AALDH1A1GAALDLR | |
| SCHEMBL8396478 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AALDH1A1GAALDLR | |
| SCHEMBL8393679 | 0.73 | ACHE (0.66) | SMN1; SMN2RAB9AALDH1A1GAALDLR | |
| SCHEMBL8391413 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AALDH1A1GAANPC1 | |
| SCHEMBL8393231 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AALDH1A1GAANPC1 | |
| SCHEMBL25123079 | 0.71 | SMN1; SMN2 (0.76) | SMN1; SMN2RAB9AALDH1A1GAANPC1 | |
| SCHEMBL8395225 | 0.71 | SMN1; SMN2 (0.76) | SMN1; SMN2RAB9AALDH1A1GAANPC1 | |
| SCHEMBL4522241 | 0.71 | SMN1; SMN2 (0.76) | SMN1; SMN2RAB9AALDH1A1GAANPC1 | |
| SCHEMBL6929834 | 0.71 | POLB (0.47) | SMN1; SMN2RAB9AALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502221-A | HYPOTENSIVE INTERMEDIATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5442105-A | Catalytic hydrogenation, epoxidation, reacting product with trialkylsilyl azide in the presence of a Lewis acid, hydrogenolysis | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0519763-A2 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-12-23 | — | — | EP | disclosed |