Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969139 | 0.98 | NAAA (0.42) | NAAAGBA2EPHX1TSHRPPARG | |
| SCHEMBL8969475 | 0.98 | NAAA (0.42) | NAAAGBA2EPHX1TSHRPPARG | |
| SCHEMBL8970689 | 0.98 | NAAA (0.42) | NAAAGBA2EPHX1TSHRPPARG | |
| SCHEMBL8970637 | 0.98 | NAAA (0.42) | NAAAGBA2EPHX1TSHRPPARG | |
| SCHEMBL8970078 | 0.98 | NAAA (0.42) | NAAAGBA2EPHX1TSHRPPARG | |
| SCHEMBL8969232 | 0.95 | ALDH1A1 (0.40) | NAAAGBA2TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL8970048 | 0.89 | PPM1B (0.41) | HCAR2ALDH1A1 | |
| SCHEMBL9863117 | 0.79 | ALDH1A1 (0.40) | NAAAEPHX1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9863118 | 0.77 | ALDH1A1 (0.38) | TSHRPPARGMAPK1SMN1; SMN2HCAR2 | |
| SCHEMBL1553673 | 0.72 | NAAA (0.55) | NAAAEPHX1TSHRPPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |