Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969944 | 0.99 | FDFT1 (0.48) | FDFT1CHRM5CHRM1CHRM3EPHX2 | |
| SCHEMBL8968777 | 0.97 | FDFT1 (0.49) | FDFT1CHRM5CHRM1CHRM3EPHX2 | |
| SCHEMBL8969731 | 0.94 | FDFT1 (0.55) | FDFT1CHRM5CHRM1CHRM3EPHX2 | |
| SCHEMBL8968794 | 0.85 | FDFT1 (0.67) | FDFT1CHRM5CHRM1CHRM3 | |
| SCHEMBL8421697 | 0.84 | FDFT1 (0.43) | FDFT1EPHX2PDE3BPDE3AP2RY12 | |
| SCHEMBL8969838 | 0.83 | FDFT1 (0.56) | FDFT1CHRM5CHRM1CHRM3FAAH | |
| SCHEMBL8417676 | 0.82 | FDFT1 (0.44) | FDFT1EPHX2FAAHMGLL | |
| SCHEMBL27459364 | 0.80 | FDFT1 (0.75) | FDFT1 | |
| SCHEMBL27486672 | 0.80 | FDFT1 (0.74) | FDFT1 | |
| SCHEMBL8418531 | 0.78 | FDFT1 (0.37) | FDFT1EPHX2PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | claimed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |