Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | MGLL | Q99685 | 4/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968794 | 0.91 | FDFT1 (0.67) | FDFT1CHRM5CHRM1CHRM3 | |
| SCHEMBL8969731 | 0.89 | FDFT1 (0.55) | FDFT1CHRM5CHRM1CHRM3AKR1C3 | |
| SCHEMBL8968777 | 0.84 | FDFT1 (0.49) | FDFT1FAAHMGLLCHRM5CHRM1 | |
| SCHEMBL8970299 | 0.83 | FDFT1 (0.49) | FDFT1FAAHMGLLCHRM5CHRM1 | |
| SCHEMBL8969944 | 0.83 | FDFT1 (0.48) | FDFT1FAAHMGLLCHRM5CHRM1 | |
| SCHEMBL27486671 | 0.82 | FDFT1 (0.83) | FDFT1 | |
| SCHEMBL8417632 | 0.76 | FDFT1 (0.60) | FDFT1AKR1C3AKR1C2 | |
| SCHEMBL8968715 | 0.72 | FDFT1 (1.00) | FDFT1 | |
| SCHEMBL8970179 | 0.71 | FDFT1 (0.85) | FDFT1 | |
| SCHEMBL27501580 | 0.70 | FDFT1 (0.84) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | claimed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |