Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969838 | 0.91 | FDFT1 (0.56) | FDFT1CHRM5CHRM1CHRM3 | |
| SCHEMBL8969731 | 0.91 | FDFT1 (0.55) | FDFT1HRH3CHRM5CHRM1CHRM3 | |
| SCHEMBL8968777 | 0.86 | FDFT1 (0.49) | FDFT1CHRM5CHRM1CHRM3 | |
| SCHEMBL8970299 | 0.85 | FDFT1 (0.49) | FDFT1CHRM5CHRM1CHRM3 | |
| SCHEMBL8969944 | 0.84 | FDFT1 (0.48) | FDFT1CHRM5CHRM1CHRM3ALDH1A1 | |
| SCHEMBL8417632 | 0.84 | FDFT1 (0.60) | FDFT1HRH3CYP4F2CYP4A11CYP4Z1 | |
| SCHEMBL8968715 | 0.80 | FDFT1 (1.00) | FDFT1 | |
| SCHEMBL9282332 | 0.77 | FDFT1 (0.76) | FDFT1HRH3CYP4F2CYP4A11CASR | |
| SCHEMBL8419593 | 0.75 | FDFT1 (0.49) | FDFT1CYP4Z1ALDH1A1 | |
| SCHEMBL8420013 | 0.74 | FDFT1 (0.48) | FDFT1HRH3CYP4F2CYP4A11CYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | claimed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |