Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12589655 | 0.88 | KMT2A (0.47) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL2761304 | 0.83 | KMT2A (0.39) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL2761303 | 0.83 | KMT2A (0.39) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL5132662 | 0.80 | KMT2A (0.51) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL8970162 | 0.78 | CHRM2 (0.39) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL8970231 | 0.75 | KMT2A (0.47) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL8969828 | 0.75 | ALDH1A1 (0.39) | KMT2ANPSR1 | |
| SCHEMBL8970369 | 0.72 | NAAA (0.42) | — | |
| SCHEMBL12972645 | 0.72 | KMT2A (0.43) | KMT2ANPSR1KDM4ECHRM2CHRM1 | |
| SCHEMBL8969171 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |