Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968464 | 0.83 | ACHE (0.50) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL8969481 | 0.83 | ACHE (0.50) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL8968353 | 0.83 | ACHE (0.56) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL8968404 | 0.83 | ACHE (0.47) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL8969172 | 0.82 | ACHE (0.54) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL8968919 | 0.82 | ACHE (0.48) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL8968416 | 0.82 | ACHE (0.48) | ACHEMEN1KMT2AHDAC6NPC1 | |
| SCHEMBL8968889 | 0.78 | ACHE (0.50) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL5511715 | 0.77 | ALDH1A1 (0.60) | ACHETP53MEN1KMT2AHDAC6 | |
| SCHEMBL9387899 | 0.77 | MEN1 (0.68) | ACHEMEN1KMT2AHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |