SCHEMBL8970478

SCHEMBL8970478

C=C(CCC(Cl)OC(C)=O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
TET2 Q6N021 3/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
ALOX15 P16050 1/20 0.31
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11411703 0.81 TET2 (0.42) TSHRTET2TET3TET1ALOX15
SCHEMBL130961 0.78 TSHR (0.32) TSHRTET2TET3TET1ALOX15
SCHEMBL2111108 0.75 TSHR (0.30) TSHR
SCHEMBL4939024 0.74 TET2 (0.37) TET2TET3TET1ALOX15GRIK1
SCHEMBL5544540 0.73 TET2 (0.39) TET2TET3TET1ALOX15GRIK1
SCHEMBL11394428 0.73 TSHR (0.46) TSHR
SCHEMBL4451563 0.73
SCHEMBL5426723 0.71 TET2 (0.43) TET2TET3TET1ALOX15GRIK1
SCHEMBL202087 0.71
SCHEMBL7556851 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0395136-B1 Radiation-sensitive composition and use thereof in the preparation of electrochemical ion sensors JOHNSON & JOHNSON CLIN DIAG (US) 1996-03-20 EP disclosed
US-5240586-A Coated on a sensor; exposure; removal of non-exposed areas EASTMAN KODAK COMPANY (US) 1993-08-31 US disclosed
EP-0395136-A2 Radiation-sensitive composition and use thereof in the preparation of electrochemical ion sensors Johnson & Johnson Clinical Diagnostics, Inc. (US) 1990-10-31 EP disclosed
EP-0029358-B1 PHOTOCROSSLINKABLE COMPOSITIONS AND PRESENSITISED LITHO PLATES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-09-28 EP disclosed
EP-0029358-A1 Photocrosslinkable compositions and presensitised litho plates EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-05-27 EP disclosed
US-4229519-A CATIONIC ADDITION POLYMER EASTMAN KODAK COMPANY (US) 1980-10-21 US disclosed
US-4141867-A CHLOROACETOXYALKYL ACRYLATE INTERNAL CROSSLINKING AGENT, POLYAMINOAMINE DEUTSCHE TEXACO AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed