SCHEMBL2111108

SCHEMBL2111108

C=C(CCC(C#N)OC(C)=O)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2110180 0.92 EPHX2 (0.34)
SCHEMBL1985287 0.91 EPHX2 (0.36)
SCHEMBL27768509 0.78 TSHR (0.34) TSHR
SCHEMBL7175617 0.76 TSHR (0.36) TSHR
SCHEMBL8965442 0.76 TSHR (0.36) TSHR
SCHEMBL8970478 0.75 TSHR (0.32) TSHR
Benzene SCHEMBL8964846 0.75 SLC6A3 (0.34) TSHR
SCHEMBL130961 0.75 TSHR (0.32) TSHR
SCHEMBL7183665 0.74 EPHX2 (0.41) TSHR
SCHEMBL1142724 0.74 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795343-B2 Polymer composition ROHM AND HAAS COMPANY (US) 2010-09-14 US claimed
US-20080139737-A1 Polymer composition ROHM AND HAAS COMPANY 2008-06-12 US claimed
EP-0492210-B1 Polymer-coated concrete BASF AG (DE) 1994-09-21 EP claimed
EP-0492210-A1 Polymer-coated concrete BASF Aktiengesellschaft (DE) 1992-07-01 EP claimed
EP-2518109-B1 Stabilised aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating ROHM & HAAS (US) 2015-06-17 EP disclosed
US-8815997-B2 Aqueous compositions comprising ion exchange resins that deliver paint and primer properties in a coating ROHM AND HAAS COMPANY (US) 2014-08-26 US disclosed
US-8791190-B2 Stabilized aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating ROHM AND HAAS COMPANY (US) 2014-07-29 US disclosed
EP-2518116-B1 Aqueous compositions comprising ion exchange resins that deliver paint and primer properties in a coating ROHM & HAAS (US) 2014-07-02 EP disclosed
US-20120277333-A1 STABILIZED AQUEOUS COMPOSITIONS COMPRISING CATIONIC POLYMERS THAT DELIVER PAINT AND PRIMER PROPERTIES IN A COATING ROHM AND HAAS COMPANY 2012-11-01 US disclosed
US-20120277334-A1 AQUEOUS COMPOSITIONS COMPRISING ION EXCHANGE RESINS THAT DELIVER PAINT AND PRIMER PROPERTIES IN A COATING ROHM AND HAAS COMPANY 2012-11-01 US disclosed
EP-2518116-A1 Aqueous compositions comprising ion exchange resins that deliver paint and primer properties in a coating Rohm and Haas Company (US) 2012-10-31 EP disclosed
EP-2518109-A1 Stabilised aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating Rohm and Haas Company (US) 2012-10-31 EP disclosed
US-20090171005-A1 Scrub and stain-resistant coating ROHM AND HAAS COMPANY 2009-07-02 US disclosed
US-20090004394-A1 Aqueous polymeric composition KOLLER ANNE DENISE 2009-01-01 US disclosed
US-20080139737-A1 Polymer composition ROHM AND HAAS COMPANY 2008-06-12 US disclosed
US-20070238827-A1 Dirt pickup resistant coating binder having high adhesion to substrates BRADY JEAN M 2007-10-11 US disclosed
EP-0497101-B1 Fibre-based moulding compound BASF AG (DE) 1995-09-06 EP disclosed
EP-0492210-B1 Polymer-coated concrete BASF AG (DE) 1994-09-21 EP disclosed
EP-0497101-A2 Fibre-based moulding compound BASF Aktiengesellschaft (DE) 1992-08-05 EP disclosed
EP-0492210-A1 Polymer-coated concrete BASF Aktiengesellschaft (DE) 1992-07-01 EP disclosed