Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901920 | 0.87 | RAB9A (0.58) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL16244206 | 0.86 | RAB9A (0.57) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL2720399 | 0.86 | RAB9A (0.57) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL31445349 | 0.86 | RAB9A (0.57) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11349059 | 0.84 | RAB9A (0.56) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL9682910 | 0.84 | RAB9A (0.56) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL21688271 | 0.77 | RAB9A (0.52) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL30816126 | 0.74 | ALDH1A1 (0.44) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL8636039 | 0.74 | RAB9A (0.44) | RAB9ATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL7397055 | 0.73 | RAB9A (0.44) | RAB9ATSHRMAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585392-A | TREATING OR PREVENTING STROKES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5506246-A | Method for treating depression using substituted aminomethyltetralins and their heterocyclic analogues | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |
| US-5300523-A | Binding serotonin receptors, treating nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5137901-A | For binding 5-HT 1 receptors; treating central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| US-4279910-A | Quinazoline therapeutic agents | PFIZER INC. (US) | 1981-07-21 | — | — | US | disclosed |