Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9067525 | 0.77 | SLC22A6 (0.36) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL5057193 | 0.76 | SLC22A6 (0.39) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL21819661 | 0.75 | SLC22A6 (0.35) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL6418946 | 0.75 | TET2 (0.46) | — | |
| SCHEMBL1756480 | 0.75 | SLC22A6 (0.35) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL4319153 | 0.70 | TDP1 (0.43) | SLC22A6TDP1ADRA1ASMN1; SMN2MAPT | |
| SCHEMBL5003457 | 0.70 | TDP1 (0.43) | SLC22A6TDP1ADRA1ASMN1; SMN2MAPT | |
| SCHEMBL304303 | 0.69 | SLC22A6 (0.50) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL258152 | 0.69 | SLC22A6 (0.50) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL5077944 | 0.69 | SLC22A6 (0.50) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536732-A | REDUCING INFECTIOUSNESS OF HIV | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5252587-A | Viricides, aids therapy, antidiabetic agent | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0454580-A2 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0453692-A1 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0008130-B1 | ORGANOSILICON COUMPOUNDS FOR THE TREATMENT OF HYPERTENSION AND TUMORS | Shin-Etsu Chemical Co., Ltd. (JP) | 1982-12-15 | — | — | EP | disclosed |
| US-4336251-A | Medicaments containing an organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| US-4336251-A | Medicaments containing an organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| EP-0008130-A1 | Organosilicon coumpounds for the treatment of hypertension and tumors | Shin-Etsu Chemical Co., Ltd. (JP) | 1980-02-20 | — | — | EP | disclosed |
| EP-0008130-A1 | Organosilicon coumpounds for the treatment of hypertension and tumors | Shin-Etsu Chemical Co., Ltd. (JP) | 1980-02-20 | — | — | EP | disclosed |