Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819661 | 1.00 | SLC22A6 (0.35) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL27996315 | 0.79 | SLC22A6 (0.36) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL27714061 | 0.78 | SLC22A6 (0.32) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL8970587 | 0.75 | SLC22A6 (0.41) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL15437626 | 0.72 | LMNA (0.40) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL21819624 | 0.71 | MAPT (0.40) | MAPTCYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL9067525 | 0.70 | SLC22A6 (0.36) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL633699 | 0.70 | PGD (0.39) | PGD | |
| SCHEMBL28215085 | 0.69 | TSHR (0.34) | PGDTSHR | |
| SCHEMBL5057193 | 0.69 | SLC22A6 (0.39) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591531-B1 | PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A | SHOWA DENKO KK (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-7943351-B2 | Method for acyltransferase reaction using acyl coenzyme A | SHOWA DENKO K.K. (JP) | 2011-05-17 | — | — | US | disclosed |
| US-20090111153-A1 | METHOD FOR ACYLTRANSFERASE REACTION USING ACYL COENZYME A | SHOWA DENKO K.K. | 2009-04-30 | — | — | US | disclosed |
| US-7476521-B2 | acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester | SHOWA DENKO K.K. (JP) | 2009-01-13 | — | — | US | disclosed |
| US-20060148048-A1 | acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester | SHOWA DENKO K.K. (JP) | 2006-07-06 | — | — | US | disclosed |
| EP-1591531-A1 | PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A | Showa Denko K.K. (JP) | 2005-11-02 | — | — | EP | disclosed |