Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8971204 | 0.99 | PPARG (0.50) | PPARGPPARASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8970668 | 0.93 | PPARG (0.47) | PPARGPPARASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8970813 | 0.92 | HTR7 (0.49) | PPARGPPARASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8970690 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3DRD1KCNA3 | |
| Hydrochloric Acid SCHEMBL8971478 | 0.87 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3DRD1KCNA3 | |
| SCHEMBL8970841 | 0.86 | PPARG (0.46) | PPARGPPARASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4589037 | 0.85 | HTR7 (0.52) | PPARGPPARAHTR7KCNA3KDM4E | |
| SCHEMBL8971631 | 0.83 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3DRD1KDM4E | |
| SCHEMBL4589309 | 0.83 | HTR7 (0.53) | PPARGPPARAHTR7KCNA3KDM4E | |
| Hydrochloric Acid SCHEMBL8970739 | 0.82 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3DRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490560-B1 | 1,2,3,6-Tetrahydropyridine derivatives | RICHTER GEDEON VEGYESZET (HU) | 1996-03-20 | — | — | EP | claimed |