Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8971478 | 0.99 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL8970731 | 0.93 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL8971041 | 0.92 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL8971631 | 0.92 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| Hydrochloric Acid SCHEMBL8970739 | 0.91 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL8971350 | 0.90 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3SIGMAR1HTR1A | |
| SCHEMBL8970627 | 0.88 | PPARG (0.51) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL8970859 | 0.88 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL9092085 | 0.88 | SIGMAR1 (0.58) | SLC6A4SLC6A2SLC6A3SIGMAR1HTR1A | |
| SCHEMBL9093691 | 0.88 | SIGMAR1 (0.51) | SLC6A4SLC6A2SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490560-B1 | 1,2,3,6-Tetrahydropyridine derivatives | RICHTER GEDEON VEGYESZET (HU) | 1996-03-20 | — | — | EP | claimed |