Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969261 | 0.94 | MGAM (0.40) | MGAMMAPTNR1H2NR1H3ALDH1A1 | |
| SCHEMBL18084487 | 0.89 | MGAM (0.44) | MGAMMAPTNR1H2NR1H3ALOX12 | |
| SCHEMBL9217667 | 0.79 | MAPT (0.47) | MGAMMAPTNR1H2NR1H3ALDH1A1 | |
| SCHEMBL11356400 | 0.79 | NR1H2 (0.50) | MGAMMAPTNR1H2NR1H3ESR1 | |
| SCHEMBL20482223 | 0.79 | NR1H2 (0.46) | MGAMNR1H2NR1H3ALDH1A1 | |
| SCHEMBL2965525 | 0.79 | MGAM (0.39) | MGAMMAPTNR1H2NR1H3ESR1 | |
| SCHEMBL4201225 | 0.79 | HDAC3 (0.39) | MGAMMAPTNR1H2NR1H3ESR1 | |
| SCHEMBL3235109 | 0.79 | MGAM (0.39) | MGAMMAPTNR1H2NR1H3ESR1 | |
| SCHEMBL7536048 | 0.79 | NR1H2 (0.46) | MGAMNR1H2NR1H3ALDH1A1 | |
| SCHEMBL28899778 | 0.79 | NR1H2 (0.46) | MGAMNR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536732-A | REDUCING INFECTIOUSNESS OF HIV | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5252587-A | Viricides, aids therapy, antidiabetic agent | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1993-10-12 | — | — | US | disclosed |