Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 15/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | LCT | P09848 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971025 | 0.92 | NAAA (0.32) | NAAAPTPN11 | |
| SCHEMBL8970853 | 0.92 | NAAA (0.32) | NAAAPTPN11 | |
| SCHEMBL8970864 | 0.88 | RARB (0.37) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8969744 | 0.87 | CNR2 (0.33) | NAAAPTPN11 | |
| SCHEMBL8970751 | 0.86 | NAAA (0.39) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8969598 | 0.86 | S1PR1 (0.33) | NAAAPTPN11FPR2 | |
| SCHEMBL8954956 | 0.84 | FPR2 (0.36) | PTPN11PTPN1PTPN6FPR2 | |
| SCHEMBL8955053 | 0.84 | FPR2 (0.36) | PTPN11PTPN1PTPN6FPR2 | |
| SCHEMBL8955134 | 0.84 | FPR2 (0.36) | PTPN11PTPN1PTPN6FPR2 | |
| SCHEMBL8955113 | 0.84 | FPR2 (0.36) | PTPN11PTPN1PTPN6FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |