Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.58 |
| ▸ | PNP | P00491 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | AHCY | P23526 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472338 | 0.89 | PDE4D (0.74) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL22300667 | 0.89 | LMNA (0.58) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL9548885 | 0.88 | PNP (0.54) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL31359569 | 0.86 | PNP (0.55) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL31359571 | 0.86 | PNP (0.55) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL13576815 | 0.86 | PNP (0.55) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL26800650 | 0.85 | PNP (0.54) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL9150000 | 0.85 | PDE4D (0.61) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL23982120 | 0.84 | PNP (0.79) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL12123492 | 0.84 | PNP (0.79) | LMNAPDE4DPDE3APNPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417999-B1 | Antiviral compounds | WELLCOME FOUND (GB) | 1996-03-13 | — | — | EP | claimed |