Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | AHCY | P23526 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958778 | 0.92 | PNP (0.46) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL25399520 | 0.91 | LMNA (0.53) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL21959765 | 0.91 | LMNA (0.49) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL26288668 | 0.91 | LMNA (0.53) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL9548819 | 0.88 | ADA (0.53) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL9548829 | 0.88 | ADA (0.53) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL8970868 | 0.88 | LMNA (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL22300667 | 0.85 | LMNA (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL13576815 | 0.85 | PNP (0.55) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL31359571 | 0.85 | PNP (0.55) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |