Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17472229 | 0.82 | CA2 (0.56) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL16535894 | 0.82 | CA2 (0.56) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL15226040 | 0.80 | CA2 (0.54) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL15226041 | 0.80 | CA2 (0.54) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL10056019 | 0.79 | CA2 (0.57) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL10055651 | 0.79 | CA2 (0.57) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL8427932 | 0.78 | CA2 (0.55) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL21345627 | 0.77 | CA2 (0.48) | CA2NAMPTTMEM97SIGMAR1HCRTR2 | |
| SCHEMBL8241735 | 0.77 | CA2 (0.48) | CA2NAMPTTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL15548662 | 0.76 | CA2 (0.50) | CA2NAMPTTMEM97SIGMAR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700918-A1 | NEW IODIZED BORON COMPOUNDS USEFUL AS X RAY CONTRASTING AGENTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRO INVESTIGACION JUSTESA IMAGEN S.A. (ES) | 1996-03-13 | — | — | EP | disclosed |