Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535894 | 0.89 | CA2 (0.56) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL15226041 | 0.87 | CA2 (0.54) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL15226040 | 0.87 | CA2 (0.54) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL10056019 | 0.86 | CA2 (0.57) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL10055651 | 0.86 | CA2 (0.57) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL8427932 | 0.84 | CA2 (0.55) | CA2NAMPTTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL15548662 | 0.83 | CA2 (0.50) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL5160066 | 0.83 | CA2 (0.50) | CA2NAMPTMTNR1ATMEM97SIGMAR1 | |
| SCHEMBL8970934 | 0.82 | CA2 (0.49) | CA2NAMPTTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL8836789 | 0.82 | CA2 (0.49) | CA2NAMPTMTNR1ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024251-A1 | THERMORESPONSIVE POLYESTERS | THE UNIVERSITY OF AKRON | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024251-A1 | THERMORESPONSIVE POLYESTERS | COASY, CD14, NCAPH | CA2 2348/4885NAMPT 3632/4885MTNR1A 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.