Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 14/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919604 | 0.82 | HRH3 (0.38) | HRH3 | |
| SCHEMBL921719 | 0.78 | KCNA3 (0.38) | HRH3 | |
| SCHEMBL6640628 | 0.78 | NPY1R (0.41) | NPY1RKMT2AHRH3 | |
| SCHEMBL5494073 | 0.77 | EED (0.47) | NPY1REEDKMT2AHRH3 | |
| SCHEMBL920509 | 0.76 | KCNA3 (0.37) | HRH3 | |
| SCHEMBL920964 | 0.76 | KCNA3 (0.37) | HRH3 | |
| SCHEMBL919876 | 0.76 | KCNA3 (0.37) | HRH3 | |
| SCHEMBL7955354 | 0.76 | KMT2A (0.54) | NPY1REEDKMT2ACHRNB2CHRNA4 | |
| SCHEMBL4462919 | 0.76 | NFE2L2 (0.57) | NPY1RKMT2AHRH3 | |
| SCHEMBL28283793 | 0.76 | NPY1R (0.57) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586490-B1 | DERIVATIVES OF PERHYDROISOINDOL, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE POULENC RORER SA (FR) | 1996-03-20 | — | — | EP | disclosed |
| WO-1992020653-A1 | NOVEL DERIVATIVES OF PERHYDROISOINDOL, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514273-A1 | New derivatives of perhydroisoindole, their preparation and pharmaceutical compositions containing them | Aventis Pharma S.A. (FR) | 1992-11-19 | — | — | EP | disclosed |