SCHEMBL8970973

SCHEMBL8970973

CCCOC1CCSC1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.34
PTPN1 P18031 1/20 0.34
PPP1CC P36873 1/20 0.34
PPP5C P53041 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970046 0.90 PPP5C (0.44) PPP5C
SCHEMBL8969295 0.89 PPP5C (0.40) PPP5C
SCHEMBL8970163 0.87 GBA1 (0.40) PPP5C
SCHEMBL8970629 0.87 GBA1 (0.40) PPP5C
SCHEMBL8970303 0.87 GBA1 (0.40) PPP5C
SCHEMBL8970296 0.87 GBA1 (0.40) PPP5C
SCHEMBL8969256 0.86 ALDH1A1 (0.35) PPM1BPTPN1PPP1CC
SCHEMBL8969585 0.78 RAB9A (0.35)
SCHEMBL8969088 0.77 SLC18A3 (0.38)
SCHEMBL8970898 0.76 CHRM2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed