SCHEMBL8971198

SCHEMBL8971198

CCCC(=O)OC1CC(=O)NC1Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.41
CTSD P07339 12/20 0.40
BCHE P06276 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971381 1.00 SLC18A3 (0.41) SLC18A3CTSDBCHE
SCHEMBL8970887 0.78 CTSD (0.37) SLC18A3CTSD
SCHEMBL8971157 0.78 CTSD (0.37) SLC18A3CTSD
SCHEMBL8970758 0.73 CTSD (0.39) SLC18A3CTSD
SCHEMBL21058110 0.71 CTSD (0.43) CTSD
SCHEMBL21058080 0.71 CTSD (0.45) CTSD
SCHEMBL22559986 0.71 CTSD (0.44) CTSD
SCHEMBL21103726 0.71 CTSD (0.45) CTSD
SCHEMBL21058081 0.71 CTSD (0.45) CTSD
SCHEMBL21058082 0.71 CTSD (0.45) CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0529483-B1 Process for the preparation of optically active 4-amino-3-hydroxycarboxylic acids LONZA AG (CH) 1996-02-28 EP disclosed
US-5352801-A Process for the production of optically-active 4-amino-3-hydroxycarboxylic acids LONZA LTD. (CH) 1994-10-04 US disclosed
US-5286650-A Process for the production of optically-active 4-amino-3-hydroxycarboxylic acids LONZA LTD. (CH) 1994-02-15 US disclosed
EP-0529483-A2 Process for the preparation of optically active 4-amino-3-hydroxycarboxylic acids LONZA AG (CH) 1993-03-03 EP disclosed