Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971157 | 0.79 | CTSD (0.37) | CTSDSLC18A3PRKCAALDH1A1MEN1 | |
| SCHEMBL8970887 | 0.79 | CTSD (0.37) | CTSDSLC18A3PRKCAALDH1A1MEN1 | |
| SCHEMBL8971381 | 0.73 | SLC18A3 (0.41) | CTSDSLC18A3 | |
| SCHEMBL8971198 | 0.73 | SLC18A3 (0.41) | CTSDSLC18A3 | |
| SCHEMBL3189185 | 0.70 | NAAA (0.52) | SLC18A3NAAAPRKCAALDH1A1MEN1 | |
| SCHEMBL3189181 | 0.70 | NAAA (0.52) | SLC18A3NAAAPRKCAALDH1A1MEN1 | |
| SCHEMBL9866747 | 0.70 | CTSD (0.60) | CTSD | |
| SCHEMBL9866742 | 0.70 | CTSD (0.60) | CTSD | |
| SCHEMBL9869456 | 0.68 | CTSD (0.35) | CTSD | |
| SCHEMBL9134369 | 0.65 | NAAA (0.73) | SLC18A3NAAALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529483-B1 | Process for the preparation of optically active 4-amino-3-hydroxycarboxylic acids | LONZA AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5352801-A | Process for the production of optically-active 4-amino-3-hydroxycarboxylic acids | LONZA LTD. (CH) | 1994-10-04 | — | — | US | disclosed |
| US-5286650-A | Process for the production of optically-active 4-amino-3-hydroxycarboxylic acids | LONZA LTD. (CH) | 1994-02-15 | — | — | US | disclosed |
| EP-0529483-A2 | Process for the preparation of optically active 4-amino-3-hydroxycarboxylic acids | LONZA AG (CH) | 1993-03-03 | — | — | EP | disclosed |