Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675402 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8971980 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2FFAR1LMNAL3MBTL1CA1 | |
| SCHEMBL846131 | 0.69 | NR1H4 (0.71) | RXRARXRBRXRGFFAR1NR1H4 | |
| SCHEMBL69746 | 0.68 | FFAR1 (0.81) | SMN1; SMN2FFAR1LMNAL3MBTL1CA1 | |
| SCHEMBL23665763 | 0.67 | CA1 (0.53) | RXRARXRBRXRGFFAR1LMNA | |
| SCHEMBL18902133 | 0.67 | FFAR1 (0.61) | SMN1; SMN2FFAR1LMNAL3MBTL1CA1 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.66 | FFAR1 (0.77) | SMN1; SMN2FFAR1LMNAL3MBTL1CA1 | |
| SCHEMBL8971390 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNACA2ALDH1A1NPSR1 | |
| SCHEMBL27925098 | 0.66 | FFAR1 (0.59) | RXRARXRBRXRGFFAR1NR1H4 | |
| SCHEMBL6461702 | 0.65 | FFAR1 (0.53) | RXRARXRBRXRGFFAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527824-A | ADMINISTERING IN THE TREATMENT OF ASTHMA, PSORIASIS AND ALLERGIC CONDITIONS | RIKER LABORATORIES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5498745-A | ANTIALLERGEN INTERMEDIATES, INHIBITORS OF LEUKOTRIENES, LIPOXYGENASE INHIBITORS | RIKER LABORATORIES, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5495043-A | ANTIALLERGENS | RIKER LABORATORIES, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5416113-A | Bronchodilators | RIKER LABORATORIES, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| US-5347036-A | Antiallergens | RIKER LABORATORIES, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5237070-A | Antiallergens, inhibiting bronchoconstriction | RIKER LABORATORIES, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0212848-B1 | SUBSTITUTED-DI-T-BUTYLPHENOLS | RIKER LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0212848-A2 | Substituted-di-t-butylphenols | RIKER LABORATORIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |