Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675402 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2PKMATMALDH1A1KMT2A | |
| SCHEMBL10359067 | 0.79 | ESR1 (0.40) | SMN1; SMN2HCAR2PKMCA12AKR1B10 | |
| SCHEMBL1814868 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2PKMMAPK1THRBATM | |
| SCHEMBL8971203 | 0.73 | RXRA (0.45) | SMN1; SMN2CA1CA2CYP26A1CYP26B1 | |
| SCHEMBL12103681 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2CA1CA2TYRCYP1A2 | |
| SCHEMBL10364440 | 0.70 | MAPT (0.55) | SMN1; SMN2PKMKDM4ETHRBALDH1A1 | |
| SCHEMBL846833 | 0.69 | CYP1A2 (0.75) | SMN1; SMN2HCAR2PKMCA12AKR1B10 | |
| SCHEMBL4001354 | 0.69 | CYP1A2 (0.75) | SMN1; SMN2HCAR2PKMCA12AKR1B10 | |
| SCHEMBL818742 | 0.69 | CYP1A2 (0.75) | SMN1; SMN2HCAR2PKMCA12AKR1B10 | |
| SCHEMBL713717 | 0.68 | HCAR2 (0.81) | SMN1; SMN2HCAR2PKMCA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527824-A | ADMINISTERING IN THE TREATMENT OF ASTHMA, PSORIASIS AND ALLERGIC CONDITIONS | RIKER LABORATORIES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5498745-A | ANTIALLERGEN INTERMEDIATES, INHIBITORS OF LEUKOTRIENES, LIPOXYGENASE INHIBITORS | RIKER LABORATORIES, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5495043-A | ANTIALLERGENS | RIKER LABORATORIES, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5416113-A | Bronchodilators | RIKER LABORATORIES, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| US-5347036-A | Antiallergens | RIKER LABORATORIES, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5237070-A | Antiallergens, inhibiting bronchoconstriction | RIKER LABORATORIES, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0212848-B1 | SUBSTITUTED-DI-T-BUTYLPHENOLS | RIKER LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0212848-A2 | Substituted-di-t-butylphenols | RIKER LABORATORIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |