Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 7/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971210 | 0.87 | EPHX1 (0.44) | GNAO1GNAI3GNAI1EPHX1EPHX2 | |
| SCHEMBL23533551 | 0.86 | KCNH2 (0.51) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Hydrochloric Acid SCHEMBL29966132 | 0.85 | GNAO1 (0.53) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Acetic Acid SCHEMBL30330029 | 0.83 | KCNH2 (0.51) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Acetic Acid SCHEMBL29252423 | 0.81 | KCNH2 (0.54) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Acetic Acid SCHEMBL30330365 | 0.81 | KCNH2 (0.54) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Acetic Acid SCHEMBL30330974 | 0.81 | KCNH2 (0.54) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Acetic Acid SCHEMBL30329903 | 0.81 | KCNH2 (0.54) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| Acetic Acid SCHEMBL29252369 | 0.81 | KCNH2 (0.54) | GNAO1GNAI3GNAI1KCNH2BCHE | |
| SCHEMBL7327464 | 0.81 | EPHX1 (0.47) | GNAO1GNAI3GNAI1KCNH2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |