Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23533426 | 0.98 | GNAO1 (0.47) | EPHX1EPHX2KCNH2GNAO1GNAI3 | |
| SCHEMBL23533551 | 0.95 | KCNH2 (0.51) | EPHX1EPHX2KCNH2GNAO1GNAI3 | |
| Hydrochloric Acid SCHEMBL29966132 | 0.93 | GNAO1 (0.53) | KCNH2GNAO1GNAI3GNAI1CHRM1 | |
| SCHEMBL13934478 | 0.89 | SMN1; SMN2 (0.46) | EPHX1EPHX2KCNH2GNAO1GNAI3 | |
| SCHEMBL25133751 | 0.84 | CYP1A2 (0.40) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| Acetic Acid SCHEMBL30329912 | 0.82 | EPHX1 (0.47) | EPHX1EPHX2KCNH2GNAO1GNAI3 | |
| SCHEMBL12442951 | 0.82 | KCNH2 (0.45) | EPHX1EPHX2KCNH2GNAO1GNAI3 | |
| SCHEMBL13472647 | 0.81 | EPHX1 (0.47) | EPHX1EPHX2GNAO1GNAI3GNAI1 | |
| SCHEMBL1762876 | 0.81 | SMN1; SMN2 (0.52) | EPHX1EPHX2 | |
| SCHEMBL8971215 | 0.81 | GNAO1 (0.50) | EPHX1EPHX2KCNH2GNAO1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230107538-A1 | CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2023-04-06 | — | — | US | disclosed |
| US-20230107538-A1 | CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2023-04-06 | — | — | US | disclosed |
| EP-4076649-A1 | CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2022-10-26 | — | — | EP | disclosed |
| CN-114828958-A | Cycloalkyl-containing carboxylic acids and use thereof | 里米诺生物科学有限公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021124272-A1 | CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2021-06-24 | — | — | WO | disclosed |
| EP-2840083-B1 | NITROGENATED BICYCLIC AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | IRM LLC (BM) | 2007-06-28 | — | — | US | disclosed |
| EP-0684947-A1 | AMIDE COMPOUNDS WITH PHARMACOLOGICAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019344-A1 | AMIDE COMPOUNDS WITH PHARMACOLOGICAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | KIT, PRKCH, PRKCE | EPHX1 1817/4885EPHX2 2063/4885KCNH2 837/4885 |
| US-20230107538-A1 | CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF | HCCS, CCL11, BCAT1 | EPHX1 2180/4885EPHX2 2009/4885KCNH2 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.