Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939788 | 0.84 | SLC6A9 (0.69) | SLC6A9SLC6A4HRH3MEN1KMT2A | |
| SCHEMBL8971243 | 0.84 | SLC6A9 (0.44) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL7395775 | 0.83 | SLC6A4 (0.65) | SLC6A9SLC6A4HRH3MEN1KMT2A | |
| SCHEMBL6013413 | 0.82 | SLC6A9 (0.80) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 | |
| SCHEMBL8971664 | 0.81 | SLC6A4 (0.77) | SLC6A9SLC6A4HRH3MEN1KMT2A | |
| SCHEMBL13780465 | 0.80 | SLC6A9 (0.77) | SLC6A9SLC6A4HRH3MEN1KMT2A | |
| Oxalic Acid SCHEMBL7317614 | 0.80 | SLC6A4 (0.88) | SLC6A9SLC6A4HRH3MEN1KMT2A | |
| SCHEMBL7943023 | 0.80 | SLC6A9 (0.72) | SLC6A9SLC6A4HRH3MEN1KMT2A | |
| SCHEMBL1171367 | 0.79 | SLC6A9 (1.00) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 | |
| SCHEMBL15127607 | 0.79 | SLC6A9 (1.00) | SLC6A9SLC6A4HRH3CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545425-B1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-03-20 | — | — | EP | claimed |
| US-5229417-A | Obsessive compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | claimed |
| EP-0545425-B1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5268468-A | Or optical isomers thereof | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-12-07 | — | — | US | disclosed |
| US-5229417-A | Obsessive compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0545425-A1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-09 | — | — | EP | disclosed |