Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971240 | 0.84 | SLC6A9 (0.66) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL8971666 | 0.81 | SLC6A4 (0.49) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL1171368 | 0.79 | SLC6A9 (0.68) | SLC6A9 | |
| SCHEMBL8971145 | 0.77 | SLC6A4 (0.51) | SLC6A9SLC6A4HRH3 | |
| Fumaric Acid SCHEMBL9445703 | 0.76 | SLC6A9 (0.47) | SLC6A9SLC6A4HRH3PPARG | |
| SCHEMBL7307681 | 0.73 | SLC6A4 (0.48) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL8761190 | 0.72 | PPARG (0.48) | SLC6A4HRH3PPARG | |
| SCHEMBL2723434 | 0.71 | SLC6A4 (0.66) | SLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL15821156 | 0.70 | SLC6A2 (0.67) | SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL7306543 | 0.70 | KDM4E (0.61) | SLC6A9SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229417-A | Obsessive compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | claimed |
| EP-0545425-B1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5268468-A | Or optical isomers thereof | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-12-07 | — | — | US | disclosed |
| US-5229417-A | Obsessive compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0545425-A1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-09 | — | — | EP | disclosed |