Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 6/20 | 0.44 |
| ▸ | BRS3 | P32247 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871657 | 0.89 | SLC6A3 (0.53) | SLC6A3SLC6A4LTB4R2SLC6A2BCL2L1 | |
| SCHEMBL8872298 | 0.81 | SLC6A3 (0.50) | SLC6A3SLC6A4LTB4R2SLC6A2BCL2L1 | |
| SCHEMBL8873666 | 0.80 | SLC6A3 (0.57) | SLC6A3SLC6A4LTB4R2SLC6A2BCL2L1 | |
| SCHEMBL8874327 | 0.79 | SLC6A3 (0.56) | SLC6A3SLC6A4LTB4R2SLC6A2BCL2L1 | |
| SCHEMBL8872457 | 0.77 | TSHR (0.48) | LTB4R2BCL2L1KDM4EKMT2A | |
| SCHEMBL14326964 | 0.77 | SLC6A3 (0.69) | SLC6A3SLC6A4LTB4R2SLC6A2BDKRB1 | |
| SCHEMBL3112718 | 0.77 | SLC6A3 (0.69) | SLC6A3SLC6A4LTB4R2SLC6A2BDKRB1 | |
| SCHEMBL29979869 | 0.77 | SLC6A3 (0.69) | SLC6A3SLC6A4LTB4R2SLC6A2BDKRB1 | |
| SCHEMBL7175089 | 0.76 | SLC6A3 (0.63) | SLC6A3SLC6A4LTB4R2SLC6A2BDKRB1 | |
| SCHEMBL2642187 | 0.76 | SLC6A3 (0.67) | SLC6A3SLC6A4LTB4R2SLC6A2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |