Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.57 |
| ▸ | F2 | P00734 | 6/20 | 0.52 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348953 | 0.88 | ITGB3 (0.73) | ITGB3ITGA2BPRSS1HDAC1HDAC8 | |
| SCHEMBL7352921 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7387875 | 0.86 | ITGB3 (0.76) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9710588 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7390380 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL8971461 | 0.86 | ITGB3 (0.40) | ITGB3ITGA2BHDAC1HDAC8PLA2G2A | |
| SCHEMBL7349227 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BF2 | |
| SCHEMBL7351137 | 0.84 | ITGB3 (0.63) | ITGB3ITGA2BPLAUHPNPLA2G2A | |
| SCHEMBL7380948 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7386054 | 0.82 | ITGB3 (0.76) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |