Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.60 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386530 | 0.88 | ITGB3 (0.74) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7378671 | 0.86 | ITGB3 (0.76) | ITGB3ITGA2BPRSS1ST14 | |
| SCHEMBL7387875 | 0.86 | ITGB3 (0.76) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7390380 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9710588 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7380956 | 0.83 | CYP4Z1 (0.43) | ITGB3ITGA2BGAAMAPK1NPSR1 | |
| SCHEMBL8971449 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7380002 | 0.82 | ITGB3 (0.63) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7385655 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7386054 | 0.81 | ITGB3 (0.76) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | claimed |
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |