Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842819 | 0.80 | ACHE (0.35) | ACHETSHRPPARDTP53TDP1 | |
| SCHEMBL9337737 | 0.77 | ACHE (0.33) | ACHETSHR | |
| SCHEMBL9340199 | 0.76 | ACHE (0.33) | ACHETSHR | |
| SCHEMBL9336312 | 0.76 | ACHE (0.33) | ACHETSHRPPARDMEN1KMT2A | |
| SCHEMBL491513 | 0.74 | TSHR (0.54) | ACHETSHRPPARDTP53TDP1 | |
| SCHEMBL9337971 | 0.74 | TSHR (0.38) | ACHETSHR | |
| SCHEMBL7790759 | 0.72 | TSHR (0.41) | ACHETSHRPPARDTP53TDP1 | |
| SCHEMBL8971372 | 0.72 | CYP1A2 (0.44) | TSHRPPARDMEN1KMT2A | |
| SCHEMBL10343591 | 0.71 | MEN1 (0.38) | ACHETSHRMEN1KMT2A | |
| SCHEMBL11726422 | 0.71 | PPARD (0.57) | ACHETSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567840-A | AS 4-AMINOBUTYRIC ACID AGONIST; MUSCLE RELAXANTS | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5461040-A | Therapy of spinal spacticity, multiple sclerosis, cerebral palsy, trigeminus neuralgia, drug withdrawal, pain | CIBA-GEIGY CORPORATION (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0399949-B1 | Substituted aminoalkylphosphinic acids | CIBA GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |
| US-5281747-A | Pharmaceuticals | CIBA-GEIGY CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0399949-A1 | Substituted aminoalkylphosphinic acids | CIBA-GEIGY AG (CH) | 1990-11-28 | — | — | EP | disclosed |