Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971558 | 1.00 | CYP11B1 (0.36) | CYP11B1CYP11B2CHKARARBPSEN1 | |
| SCHEMBL8453499 | 0.94 | MAOA (0.38) | CYP11B1CYP11B2CHKARARBPSEN1 | |
| SCHEMBL8453505 | 0.94 | MAOA (0.38) | CYP11B1CYP11B2CHKARARBPSEN1 | |
| SCHEMBL8451717 | 0.92 | RARB (0.41) | CYP11B1CYP11B2CHKARARBGPR84 | |
| SCHEMBL8451708 | 0.92 | RARB (0.41) | CYP11B1CYP11B2CHKARARBGPR84 | |
| SCHEMBL8452670 | 0.92 | CYP11B1 (0.35) | CYP11B1CYP11B2CHKARARBPSEN1 | |
| SCHEMBL8452674 | 0.92 | CYP11B1 (0.35) | CYP11B1CYP11B2CHKARARBPSEN1 | |
| SCHEMBL8453479 | 0.91 | RARB (0.46) | CYP11B1CYP11B2RARBGPR84HTR2A | |
| SCHEMBL8453476 | 0.91 | RARB (0.46) | CYP11B1CYP11B2RARBGPR84HTR2A | |
| SCHEMBL8453689 | 0.90 | RARB (0.47) | RARBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511487-B1 | Electro-optical liquid crystal system | MERCK PATENT GMBH (DE) | 1996-05-29 | — | — | EP | disclosed |
| EP-0700983-A2 | Electrooptical liquid crystal system | MERCK PATENT GmbH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5323251-A | Liquid crystals dispersed in isotropic, transparent polymer matrix having Swiss cheese morphology; irradiation polymerization, curing | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-21 | — | — | US | disclosed |
| EP-0511487-A1 | Electro-optical liquid crystal system | MERCK PATENT GmbH (DE) | 1992-11-04 | — | — | EP | disclosed |