SCHEMBL897158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL897744	0.85	ALK (0.50)	ALKCCNB2CDK1CCNB1GSK3B
	SCHEMBL16775676	0.84	ALK (0.47)	ALKTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL27087566	0.83	ALK (0.47)	ALKCCNB2CDK1CCNB1GSK3B
	SCHEMBL27087539	0.83	ALK (0.48)	ALKTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL1755813	0.82	ALK (0.44)	ALKTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL27087629	0.81	ALK (0.45)	ALKCCNB2CDK1CCNB1GSK3B
	SCHEMBL25446306	0.81	ALK (0.43)	ALKTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL898101	0.81	ALK (0.35)	ALKTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL897277	0.81	ALK (0.45)	ALKCCNB2CDK1CCNB1GSK3B
	SCHEMBL897541	0.80	ALK (0.61)	ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.