SCHEMBL897744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1703999	0.91	ALK (0.44)	ALKCA1CA2CA4CA6
	SCHEMBL16775676	0.90	ALK (0.47)	ALKCA1CA2CA4CA6
	SCHEMBL27087539	0.89	ALK (0.48)	ALKCA1CA2CA4CA6
	SCHEMBL27087629	0.87	ALK (0.45)	ALKCA1CA2CA4CA6
	SCHEMBL27087566	0.87	ALK (0.47)	ALKCA1CA2CA4CA6
	SCHEMBL1755813	0.86	ALK (0.44)	ALKCA1CA2CA4CA6
	SCHEMBL897145	0.86	ALK (0.63)	ALK
	SCHEMBL897158	0.85	ALK (0.46)	ALKGSK3BCCNB2CDK1CCNB1
	SCHEMBL25446306	0.84	ALK (0.43)	ALKCA1CA2CA4CA6
	SCHEMBL897277	0.84	ALK (0.45)	ALKCA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.