Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 10/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970902 | 0.86 | GAA (0.47) | GAAHTR4CYP2D6HTR3ACYP1A2 | |
| SCHEMBL7387685 | 0.84 | GAA (0.45) | GAAHTR4CYP2D6HTR3ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8971456 | 0.81 | RAB9A (0.57) | GAAHTR4CYP2D6HTR3ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8971612 | 0.78 | HTR4 (0.66) | HTR4CYP2D6HTR3ACYP3A4CYP2C9 | |
| SCHEMBL8971367 | 0.78 | HTR4 (0.69) | HTR4CYP2D6HTR3ACYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL3684761 | 0.77 | HTR4 (0.68) | HTR4CYP2D6HTR3ACYP3A4CYP2C9 | |
| SCHEMBL7714917 | 0.77 | GAA (0.54) | GAAHTR4CYP2D6HTR3ACYP1A2 | |
| SCHEMBL7355752 | 0.76 | HTR4 (0.63) | GAAHTR4CYP2D6HTR3ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7360820 | 0.75 | HTR4 (0.61) | GAAHTR4CYP2D6HTR3ACYP1A2 | |
| SCHEMBL8970785 | 0.74 | CYP2D6 (0.44) | HTR4CYP2D6HTR3ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |