Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914171 | 0.79 | HTT (0.50) | HTTTP53MAPTALDH1A1CYP1A2 | |
| SCHEMBL28911293 | 0.79 | HTT (0.50) | HTTTP53MAPTALDH1A1TDP1 | |
| SCHEMBL24900593 | 0.77 | CYP3A4 (0.53) | HTTTP53MAPTALDH1A1TDP1 | |
| SCHEMBL30204314 | 0.74 | CYP19A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCYP19A1 | |
| SCHEMBL5485827 | 0.74 | ALDH1A1 (0.45) | HTTTP53MAPTALDH1A1TDP1 | |
| SCHEMBL13043154 | 0.74 | POLB (0.53) | HTTMAPTALDH1A1CYP1A2TDP1 | |
| SCHEMBL18066875 | 0.74 | HTT (0.49) | HTTTP53MAPTALDH1A1CYP1A2 | |
| SCHEMBL24723083 | 0.73 | ALDH1A1 (0.44) | HTTMAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9354607 | 0.73 | ALDH1A1 (0.58) | HTTTP53MAPTALDH1A1CYP1A2 | |
| SCHEMBL5674584 | 0.72 | MAPT (0.69) | MAPTALDH1A1CYP1A2TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701554-A1 | NOVEL COMPOUNDS HAVING A BENZISOSELEN-AZOLINE AND -AZINE STRUCTURE, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF | OXIS INTERNATIONAL S.A. (FR) | 1996-03-20 | — | — | EP | disclosed |