Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | CRHBP | P24387 | 2/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8571681 | 0.98 | MAPT (0.67) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL8914784 | 0.90 | MAPT (0.58) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL9847298 | 0.90 | MAPT (0.58) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL17787279 | 0.90 | MMP14 (0.63) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL14063276 | 0.90 | MMP14 (0.63) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL18660127 | 0.86 | MAPT (0.77) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL16706324 | 0.85 | MAPT (0.81) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL9748257 | 0.82 | MAPT (0.62) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL6712476 | 0.82 | MAPT (1.00) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 | |
| SCHEMBL160430 | 0.82 | ALDH1A1 (0.57) | MAPTCRHBPCRHR2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018113624-A1 | FUSED IMIDAZOLE COMPOUND HAVING INDOLEAMINE 2,3-DIOXYGENASE INHIBITORY ACTIVITY | 深圳微芯生物科技有限责任公司 | 2018-06-28 | — | — | WO | disclosed |
| US-20080108576-A1 | Novel cytostatic conjugates with integrin ligands | BAYER AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-7304037-B2 | Cytostatic conjugates with integrin ligands | BAYER AKIENGESELLSCHAFT (DE) | 2007-12-04 | — | — | US | disclosed |
| US-7304037-B2 | Cytostatic conjugates with integrin ligands | BAYER AKIENGESELLSCHAFT (DE) | 2007-12-04 | — | — | US | disclosed |
| US-7220824-B1 | Integrin-mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-7220824-B1 | Integrin-mediated drug targeting | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-7148240-B2 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2006-12-12 | — | — | US | disclosed |
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI (FR) | 2004-01-15 | — | — | US | disclosed |
| US-4011173-A | MODIFIED NEMATIC MIXTURES WITH POSITIVE DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT1 | MAPT 2115/4885CRHBP 3334/4885CRHR2 4141/4885 |
| US-20080108576-A1 | Novel cytostatic conjugates with integrin ligands | ITGB3, ITGAV, ITGB5 | MAPT 4589/4885CRHBP 3477/4885CRHR2 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.