SCHEMBL8971763

SCHEMBL8971763

C=CC(CC(CC)CCCC)N1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 5/20 0.38
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 4/20 0.35
HTT P42858 2/20 0.35
USP2 O75604 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970972 0.84 MEN1 (0.37) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL29911378 0.76 ALDH1A1 (0.51) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL159735 0.76 ALDH1A1 (0.51) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL31372460 0.76 ALDH1A1 (0.51) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL29414004 0.76 ALDH1A1 (0.51) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL28375540 0.75 MEN1 (0.49) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL28374256 0.75 ALDH1A1 (0.58) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL29625375 0.75 ALDH1A1 (0.62) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL8971870 0.74 TSHR (0.48) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2
SCHEMBL22898409 0.74 MEN1 (0.51) MEN1KMT2AALDH1A1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7207252-A None JP disclosed
US-5521260-A ALKENYLNADIMIDE, VINYL COMPOUND, PHENOLIC RESIN MARUZEN PETROCHEMICAL CO., LTD. (JP) 1996-05-28 US disclosed
JP-H07207252-A SHEATHED HEATER AND SEALING COMPOUND FOR SHEATHED HEATER MARUZEN PETROCHEM CO LTD 1995-08-08 JP disclosed
US-4885346-A HEAT CURABLE; MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1989-12-05 US disclosed
US-4745166-A Heat-curable mixture containing substituted bicyclo (2.2.1) hept-5-ene-2,3-dicarboximide and polymaleimide, and ethylenically unsaturated phenolic compound CIBA-GEIGY CORPORATION (US) 1988-05-17 US disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
US-4579916-A IMPROVED STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed