SCHEMBL8971809

SCHEMBL8971809

C[Si](C)(C)O[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787435 0.86 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL297042 0.85 TSHR (0.33) ESR1ESR2
SCHEMBL13853169 0.84 ESR1 (0.35) ESR1ESR2
SCHEMBL2394267 0.80 ESR1 (0.39) ESR1ESR2NR1H2NR1H3
SCHEMBL9562976 0.79 ESR1 (0.32) ESR1ESR2
SCHEMBL2527239 0.78 ESR1 (0.38) ESR1ESR2NR1H2NR1H3
SCHEMBL2488130 0.78 ESR1 (0.38) ESR1ESR2NR1H2NR1H3
SCHEMBL13853170 0.78 ALDH1A1 (0.32)
SCHEMBL4283846 0.78
SCHEMBL21923150 0.76 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9062246-B2 Fluorescent compound, making method, and fluorescent resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-23 US disclosed
EP-2626400-B1 Fluorescent compound, making method, and fluorescent resin composition SHINETSU CHEMICAL CO (JP) 2014-10-08 EP disclosed
US-20130207041-A1 FLUORESCENT COMPOUND, MAKING METHOD, AND FLUORESCENT RESIN COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-08-15 US disclosed
EP-2626400-A1 Fluorescent compound, making method, and fluorescent resin composition Shin-Etsu Chemical Co., Ltd. (JP) 2013-08-14 EP disclosed
US-5565540-A COHYDROLYZING TRIORGANOHALOSILANE AND DIORGANODIHALOSILANE IN PRESENCE OF BASIC COMPOUND IN TWO-LAYER LIQUID SYSTEM DOW CORNING TORAY SILICON CO., LTD. (JP) 1996-10-15 US disclosed
US-5364896-A Plasticizers for silicone rubbers DOW CORNING TORAY SILICONE CO., LTD (JP) 1994-11-15 US disclosed
EP-0544257-A2 Triorganosiloxydiphenylsilanols and method for preparing same Dow Corning Toray Silicone Company, Limited (JP) 1993-06-02 EP disclosed