SCHEMBL297042

SCHEMBL297042

Cl[Si](O[Si](Cl)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LTA4H P09960 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13853170 0.87 ALDH1A1 (0.32) ALDH1A1
SCHEMBL4283846 0.87
SCHEMBL8971809 0.85 ESR1 (0.37) ESR1ESR2
SCHEMBL21923150 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL7787435 0.85 ESR1 (0.37) ESR1ESR2
SCHEMBL13853169 0.83 ESR1 (0.35) ESR1ESR2
SCHEMBL10824434 0.78 CA4 (0.38) TSHRORAI1ORAI2ORAI3TRPV6
SCHEMBL9259574 0.78 ORAI1 (0.31) TSHRORAI1ORAI2ORAI3TRPV6
SCHEMBL9562976 0.78 ESR1 (0.32) ESR1ESR2
SCHEMBL4265454 0.77 TSHR (0.33) TSHRORAI1ORAI2ORAI3TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106343-A1 ETCHING METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-05-22 WO claimed
US-20250157825-A1 ETCHING METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2025-05-15 US claimed
CN-119351137-B Crude oil desalting agent and preparation method thereof 万达集团股份有限公司 2025-03-04 CN claimed
CN-119351137-A Crude oil desalting agent and preparation method thereof 万达集团股份有限公司 2025-01-24 CN claimed
US-20240258111-A1 Surface Treatment Compositions and Methods FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2024-08-01 US claimed
US-11904352-B2 Low dielectric constant film and preparation method thereof JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2024-02-20 US claimed
CN-111565859-B Surface treatment composition and method 富士胶片电子材料美国有限公司 2022-12-30 CN claimed
US-20220314271-A1 Low Dielectric Constant Film and Preparation Method Thereof JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2022-10-06 US claimed
US-11447642-B2 Methods of using surface treatment compositions FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2022-09-20 US claimed
EP-3971320-A1 LOW DIELECTRIC CONSTANT FILM AND PREPARATION METHOD THEREOF Jiangsu Favored Nanotechnology Co., Ltd. (CN) 2022-03-23 EP claimed
US-20070077782-A1 Treatment of low dielectric constant films using a batch processing system TOKYO ELECTRON LIMITED (JP) 2007-04-05 US claimed
US-20060281934-A1 Processes for the production of polycyclic fused ring compounds FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-12-14 US claimed
US-20060281933-A1 Processes for the preparation of paclitaxel FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-12-14 US claimed
US-20060281932-A1 Processes for the preparation of docetaxel FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-12-14 US claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
US-20050215072-A1 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2005-09-29 US claimed
EP-0799852-B1 Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING (US) 2003-09-24 EP claimed
EP-1006136-A1 Solid-liquid phase interfacial polymerisation DOW CORNING CORPORATION (US) 2000-06-07 EP claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799852-A2 Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281934-A1 Processes for the production of polycyclic fused ring compounds COASY, PARG, PIN4 TSHR 4755/4885ORAI1 2870/4885ORAI2 2272/4885
US-20060281933-A1 Processes for the preparation of paclitaxel PDCD10, PDS5B, CASP10 TSHR 4488/4885ORAI1 2700/4885ORAI2 4102/4885
US-20060281932-A1 Processes for the preparation of docetaxel PDCD10, PDS5B, DHCR7 TSHR 4027/4885ORAI1 3256/4885ORAI2 3846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.