Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195015 | 0.84 | GPR84 (0.60) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL1611741 | 0.84 | TSHR (0.49) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL8971829 | 0.84 | ALDH1A1 (0.50) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL2311686 | 0.84 | GPR84 (0.51) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL11765193 | 0.84 | HTR2A (0.57) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL1610542 | 0.83 | TSHR (0.48) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL9597806 | 0.83 | HTR2A (0.59) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL1611130 | 0.83 | TSHR (0.48) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL17697931 | 0.83 | HTR2A (0.59) | TSHRALDH1A1ATMNPSR1GPR84 | |
| SCHEMBL1610356 | 0.83 | TSHR (0.48) | TSHRALDH1A1ATMNPSR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | disclosed |