SCHEMBL8971981

SCHEMBL8971981

CC(C)CC(C=O)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSMB1 P20618 1/20 0.78
PSMB5 P28074 1/20 0.78
PSMB2 P49721 1/20 0.78
CTSL P07711 11/20 0.73
CTSB P07858 7/20 0.73
CTSK P43235 6/20 0.70
CTSS P25774 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3054703 1.00 PSMB1 (0.78) PSMB1PSMB5PSMB2CTSLCTSB
SCHEMBL1014661 1.00 PSMB1 (0.78) PSMB1PSMB5PSMB2CTSLCTSB
SCHEMBL7710728 1.00 PSMB1 (0.78) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL7862424 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL14579851 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL5062219 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL14514061 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL13436259 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL2522088 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB
Mg-132 SCHEMBL2535252 0.99 PSMB1 (0.77) PSMB1PSMB5PSMB2CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543310-B1 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LTD (JP) 1996-03-27 EP disclosed
US-5395824-A Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1995-03-07 US disclosed