Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68475 | 0.91 | CHRM2 (0.38) | PPM1BPTPN1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3918398 | 0.83 | CHRM2 (0.34) | CYP3A4CYP1A2CYP2D6TSHRMAPK1 | |
| SCHEMBL17848809 | 0.82 | GABRR1 (0.33) | — | |
| SCHEMBL15055464 | 0.81 | GABRR1 (0.43) | CYP1A2CYP2D6KMT2AMEN1ALDH1A1 | |
| SCHEMBL70312 | 0.81 | GABRR1 (0.43) | CYP1A2CYP2D6KMT2AMEN1ALDH1A1 | |
| SCHEMBL8969972 | 0.78 | CHRM2 (0.34) | CYP3A4CYP1A2CYP2D6TSHRMAPK1 | |
| SCHEMBL4263557 | 0.78 | CHRM2 (0.34) | CYP3A4CYP1A2CYP2D6TSHRMAPK1 | |
| SCHEMBL16079938 | 0.78 | CHRM2 (0.34) | CYP3A4CYP1A2CYP2D6TSHRMAPK1 | |
| SCHEMBL8969007 | 0.78 | POLB (0.33) | TSHR | |
| SCHEMBL8970200 | 0.78 | PPM1B (0.42) | PPM1BPTPN1PPP1CCTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |