Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70312 | 1.00 | GABRR1 (0.43) | GABRR1GRM4CYP2C19MEN1KMT2A | |
| SCHEMBL17848809 | 0.84 | GABRR1 (0.33) | GABRR1 | |
| SCHEMBL28602961 | 0.81 | GABRR1 (0.35) | GABRR1MEN1KMT2ATDP1GABRR2 | |
| SCHEMBL29957170 | 0.81 | — | — | |
| SCHEMBL19796163 | 0.81 | GRM2 (0.36) | GABRR1MEN1KMT2AALDH1A1GABRR2 | |
| SCHEMBL8972064 | 0.81 | PPM1B (0.37) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8969007 | 0.76 | POLB (0.33) | TDP1GRM2GRM3LMNAKDM4E | |
| SCHEMBL8970065 | 0.76 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL8970200 | 0.76 | PPM1B (0.42) | ALDH1A1 | |
| SCHEMBL9031555 | 0.75 | GABRR1 (0.35) | GABRR1GABRR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |