Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001187 | 0.78 | ACE (0.41) | ACE | |
| SCHEMBL8971422 | 0.75 | ACE (0.54) | ACE | |
| Hydrochloric Acid SCHEMBL10656556 | 0.74 | ACE (0.53) | ACE | |
| Hydrochloric Acid SCHEMBL8971334 | 0.74 | ACE (0.53) | ACE | |
| SCHEMBL8972536 | 0.73 | ACE (0.46) | ACE | |
| SCHEMBL11102007 | 0.71 | SMN1; SMN2 (0.41) | ACE | |
| SCHEMBL8971348 | 0.70 | SMN1; SMN2 (0.42) | ACE | |
| SCHEMBL8971352 | 0.70 | SMN1; SMN2 (0.42) | ACE | |
| SCHEMBL10602182 | 0.69 | ACE (0.40) | ACE | |
| SCHEMBL11197520 | 0.68 | ACE (0.53) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175266-B1 | Antihypertensive derivatives | RHONE POULENC RORER PHARMA (US) | 1996-03-20 | — | — | EP | disclosed |
| US-4749698-A | Antihypertensive derivatives | RORER PHARMACEUTICAL CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0175266-A2 | Antihypertensive derivatives | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1986-03-26 | — | — | EP | disclosed |