Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070266 | 0.82 | ESR2 (0.34) | GRIN1GRIN2BESR1 | |
| SCHEMBL9020686 | 0.82 | — | — | |
| SCHEMBL8972008 | 0.80 | FGFR2 (0.38) | FGFR2FGFR1RETRXRARXRB | |
| SCHEMBL8971563 | 0.80 | GRIN1 (0.35) | FGFR2GRIN1GRIN2BFGFR1FFAR4 | |
| SCHEMBL17715213 | 0.79 | KDM1A (0.37) | FGFR2GRIN1GRIN2BFGFR1ESR1 | |
| SCHEMBL4402648 | 0.79 | KDM1A (0.37) | FGFR2GRIN1GRIN2BFGFR1ESR1 | |
| SCHEMBL22277187 | 0.79 | ESR2 (0.37) | FGFR2GRIN1GRIN2BFGFR1ESR1 | |
| SCHEMBL22277356 | 0.79 | FFAR4 (0.44) | FGFR2GRIN1GRIN2BFGFR1RXRA | |
| SCHEMBL8969206 | 0.79 | FFAR4 (0.35) | FGFR2GRIN1GRIN2BFGFR1RET | |
| SCHEMBL8970707 | 0.79 | NAAA (0.42) | FGFR2GRIN1GRIN2BFGFR1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |