Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972045 | 0.88 | KDM4E (0.44) | KDM4EADORA3ADORA1PNPLMNA | |
| SCHEMBL18844545 | 0.79 | KDM4E (0.40) | TYMPKDM4ECDK5CDK5R1 | |
| SCHEMBL18844546 | 0.78 | KDM4E (0.48) | KDM4EADORA3ADORA1POLBCDK5 | |
| SCHEMBL29776899 | 0.77 | KDM4E (0.40) | KDM4ECDK5CDK5R1 | |
| SCHEMBL18844548 | 0.77 | KDM4E (0.40) | KDM4ECDK5CDK5R1 | |
| SCHEMBL16249169 | 0.77 | KDM4E (0.40) | KDM4ECDK5CDK5R1 | |
| SCHEMBL18671306 | 0.77 | KDM4E (0.40) | KDM4ECDK5CDK5R1 | |
| SCHEMBL30002378 | 0.77 | ADORA2A (0.52) | ADORA3ADORA1 | |
| SCHEMBL17676618 | 0.77 | KDM4E (0.46) | KDM4EADORA3ADORA1POLBCDK5 | |
| SCHEMBL17943450 | 0.77 | KDM4E (0.46) | KDM4EADORA3ADORA1POLBCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541307-A | Backbone modified oligonucleotide analogs and solid phase synthesis thereof | ISIS PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |